Drugs with Side Effects of Depression

Drug use and depression are interrelated. Many drugs cause depression either directly or indirectly. Drug use can lead to addiction which can cause depression. Inversely a preexisting depression condition can lead to drug use and addiction.

Depression Is a Common Side Effect of Drug Use

Many drugs cause depression directly as a side effect of use or as a side effect of withdrawal, once physical dependence has occurred. This includes prescription drugs used as directed, illicit drugs and prescription drugs that are abused for recreational purposes.

Depression is a common indirect side effect of drug abuse and addiction. Addiction wreaks havoc in the life of the user, who then becomes depressed as a natural reaction to seeing the damage that addiction is doing to his or her life. The depression in turn often leads to further drug use, as the addict attempts to escape from and numb the pain. In extreme cases depression resulting from drug use or addiction may result in thoughts of suicide.

The Most Common Drugs That Cause Depression

Abuse of or addiction to almost any drug can cause depression indirectly. However two of the most common drugs that cause depression as a direct result of their use include the following:

  • Alcohol. Alcohol is a depressant in the sedative class of drugs. Alcohol often causes depression directly and also indirectly as a result of the consequences of problem drinking.
  • Marijuana. Although marijuana does not produce a strong physical dependence, regular use can produce psychological dependence, since marijuana alters brain chemistry. Depression is often the most noticeable withdrawal symptom when stopping use of marijuana.
  • Barbiturates (sedatives). These drugs are typically used to treat anxiety and epilepsy, but they can cause depression or worsen preexisting depression issues.
  • Benzodiazepines. These drugs are highly addictive and may cause depression, usually following long-term use or during withdrawal in cases of physical dependence.

Depression and Drug Withdrawal

Depression is a common feature of withdrawal from opiates. Opiate and opioid drugs that cause depression during withdrawal include the following:

  • Heroin
  • Morphine
  • OxyContin
  • Lortab
  • Percocet

Stimulants that may cause depression during withdrawal and detox include the following:

  • Cocaine
  • Amphetamines
  • Ritalin

Questions about Drugs and Depression?

If you have any questions about drug use, depression or treatment, call our 24 hour toll-free helpline today. We can help you assess your drug use and determine the best course of action to take for a drug-free and depression-free future.