Do Men and Women Metabolize Drugs Differently?

Do Men and Women Metabolize Drugs Differently?

Men and women metabolize drugs differently. Women tend to be smaller, have less muscle mass and smaller organs than men, but they also tend to have a higher percentage of body fat, which influences several drugs. Many drugs are inclined to attach to fatty tissue, which means they affect women more as they tend to have more fat cells. These facts mean that women metabolize certain drugs much more slowly, which means treatment must be unique between the sexes.

The way men and women metabolize drugs depends upon their differences in liver metabolism, kidney function and certain gastric enzymes. The biological differences between the sexes affect how a drug is absorbed, metabolized, distributed and excreted; as a whole, research shows that women have a greater bio-availability than men when it comes to drug absorption, meaning women’s bodies are more inviting to chemical substances than men’s. Furthermore, women tend to have slower digestive, drug-metabolizing and drug excreting systems, which means that substances stay in their systems longer than they do in men’s. Hormonal fluctuations and the menstrual cycle further influence drug metabolization.

How the Difference in Drug Metabolization Affects Men and Women

A great deal of research is being performed to examine the difference in pharmacology among men and women. Due to the biological differences between the sexes, it is imperative to study how both genders react to any drug before putting drugs on the market. Because men and women absorb, metabolize, distribute and excrete drugs differently, certain drugs will present different side effects and risks to each sex. For instance, men and women may have greater susceptibility to addiction when it comes to certain drug types. Certain drugs may increase the risks for disease, high blood pressure, heart complications or other conditions differently in men than in women, and vice versa, so a dosage that may be safe for one sex may be detrimental for the other.

Due to these differences, both genders must be cautious when taking any drug. Not all clinical trials include members of both sex, so people people must research drugs they take and their possible risks as much as possible. The lesson to be learned is that everyone responds differently to drugs, so there is no way to guarantee how a certain substance will affect everyone. Be proactive with your health by learning about what you put into your body. Furthermore, learn to recognize the signs of when you should stop taking a drug. Furthermore, women must recognize that their bodies metabolize drugs differently than men’s, so the effects of a drug may increase the risks for injury and intoxication.

Are You Looking for Sex-Specific Drug Treatment?

If you are searching for drug treatment that caters to men or women, then call our toll-free helpline now. Our admissions coordinators are available 24 hours a day to answer your questions and concerns regarding addiction, treatment and recovery. Several treatment options are available to you, and our staff can offer you as much information as you need to find recovery. Call today to begin recovery.